Myriam M. Chaumeil, PhD

Assistant Professor, UCSF
Associate Director, Biomedical NMR Laboratory

Email: [email protected]
Mailing: UCSF, Box 2530, San Francisco, CA 94143


EDUCATION

  • BS, Biology, University of Bordeaux I, France
  • MS, Biomedical Physics, University of Paris XI-Orsay, France
  • Engineer Diploma, Physics, Ecole Supérieure de Physique et de Chimie Industrielles de Paris, France
  • PhD, Medical Physics, University of Paris XI-Orsay, France
  • Postdoctoral Fellow, Radiology and Biomedical Imaging, University of California, San Francisco

BIOGRAPHY

Dr. Chaumeil is an Assistant Professor in the Departments of Physical Therapy and Rehabilitation Science and Radiology and Biomedical Imaging; she is also the Associate Director of the UCSF Biomedical NMR laboratory on the Mission Bay Campus. The goal of her research program is to develop mechanism-driven Magnetic Resonance (MR) metabolic imaging approaches for improved detection of neurological disorders and monitoring of therapeutic response. Her areas of expertise include neuroimaging, metabolism and neurological disorders.

During her PhD in Paris, Dr Chaumeil developed MR imaging techniques to investigate biomarkers of neurodegeneration and physiological brain metabolism, in animal models and humans. During her post-graduate research at UCSF, she has acquired a high level of expertise in MR metabolic imaging of neurological diseases, particularly in state-of-the-art hyperpolarized 13C MRS methods, and has build national and international recognition in this up and coming field. She joined the UCSF faculty in 2016. Amongst her numerous achievements, Dr. Chaumeil received three UCSF Surbeck Scholar Awards (2011, 2012 & 2013), the Bruce Hasegawa award for Excellence in Biomedical Imaging, and was named as a Junior Fellow of the ISMRM society. In April 2015, she was selected as the only UCSF recipient of a Cal-BRAIN seed grant award as part of the California Blueprint for Research to Advance Innovations in Neuroscience, whose goal is to integrate the search and convergence on new technologies capable of monitoring wide-scale activity in the brain.


COURSES

  • PT 419 Research Seminar

CLINICAL & RESEARCH INTERESTS

  • Metabolism
  • Metabolic Imaging
  • MR spectroscopy (MRS, 31P, 1H, 13C)
  • Hyperpolarized 13C
  • Dissolution dynamic nuclear polarization (DNP)
  • Neurological disorders
  • Multiple Sclerosis
  • Traumatic Brain Injury
  • Huntington's disease
  • Alzheimer’s disease
  • Brain tumors
  • Neuroinflammation
  • Aging
  • MR biomarkers
  • Preclinical models
  • Diagnostic imaging
  • Clinical translation

CURRENT RESEARCH

Dr. Chaumeil's laboratory is located in the Quantitative Biosciences Institute (QBI) on the fog-free and sunny UCSF Mission Bay Campus. QBI is designed to house multi-department and multi-disciplinary laboratories, foster collaborations across the biomedical and the physical sciences, in order to seek quantitative methods to address pressing problems in biology and biomedicine.

Dr. Chaumeil’s imaging research is conducted in QBI and in the UCSF Biomedical NMR lab and the Surbeck Laboratory for Advanced Imaging, which are adjacent to QBI at Mission Bay. The goal of her research program is to develop innovative, mechanism-driven MR metabolic imaging approaches for improved detection of neurological disorders and monitoring of therapeutic response. With the active support of the NIH-funded P41 Hyperpolarized 13C Resource center, Dr. Chaumeil’s work is mainly focused on the new hyperpolarized DNP-MR technology and investigates preclinical models of Multiple Sclerosis, Traumatic Brain Injury, Alzheimer’s disease and brain tumors (to date). Based on the knowledge of metabolic changes associated with these neurological disorders, Dr. Chaumeil’s team aim to develop and biologically validate new imaging agents with dramatically increased signal intensity (Hyperpolarized Probes) and optimized acquisitions strategies for diagnosis and treatment monitoring.


RECENT PUBLICATIONS

View the list on Pubmed


HONORS AND AWARDS

  • Awarded the California Blueprint for Research to Advance Innovations in Neuroscience (Cal-BRAIN) seed grant ($120,000) – Only one at UCSF (2015)
  • Annual Recipient of the Bruce Hasegawa Award for Excellence in Biomedical Imaging, UCSF (2013)
  • Margaret H. Surbeck Award Winner, UCSF (2011, 2012 and 2013)
  • Junior Fellow of the International Society of Magnetic Resonance in Medicine (ISMRM) (2012)
  • William Negendank Award Winner - ISMRM Workshop Improving Cancer Treatment with Advanced MR (2011)