The Department demonstrates scientific inquiry and critical thinking within the academic programs and in clinical practice. Faculty members participate in a variety of basic, clinical and translational research studies. Clinical and outcomes research take place in the Outpatient Physical Therapy Faculty Practice, the PhysFit Physical Therapy Health and Wellness Center, and the Human Performance Center on the Mission Bay campus. Basic science studies are carried out in laboratories on the Parnassus campus and in the Brain and Spinal Injury Center (BASIC) at San Francisco General Hospital.

Areas of research emphasis include in vivo animal models to study traumatic brain and spinal cord injury, cranial irradiation, chronic neuroinflammation, and post translational protein alterations that affect cognitive functions. A longer-term goal is to understand the mechanisms responsible for motor sensory loss after spinal cord injury and cognitive dysfunction associated with neurodegenerative diseases such as Alzheimer's disease, fronto-temporal dementia as well as traumatic brain injury, and to identify and test interventions that may improve motor, sensory, and cognitive function.

Basic and clinical studies are interdepartmental and collaborative, and occur in conjunction with colleagues at the Cancer Center and Gladstone Institute and within the Immunology Program and the Departments of Anatomy, Bioengineering, Radiology, Neurology, Neurosurgery, and Nursing. Students are integral to these research collaborations, benefiting from the multiple perspectives that collectively define and guide research directions.

The faculty are involved in a variety of basic, clinical, and translational research studies. Read more about each faculty member's research projects under the Ongoing Studies page.